Muscle pathological features and extra-muscle involvement in idiopathic inflammatory myopathies with anti-mitochondrial antibody
نویسندگان
چکیده
منابع مشابه
Juvenile idiopathic inflammatory myopathies: the value of magnetic resonance imaging in the detection of muscle involvement.
CONTEXT One of the major current challenges related to juvenile idiopathic inflammatory myopathy is the search for highly sensitive and specific non-invasive methods for diagnosis as well as for follow-up. OBJECTIVES The aim of our study was to describe typical magnetic resonance imaging findings and to investigate the usefulness of this method in detecting active muscle disease in juvenile d...
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Anti-mitochondrial antibodies, the characteristic markers of primary biliary cirrhosis, have been detected in most patients with this disease. However, the prevalence of these antibodies in inflammatory myopathies and their clinical and histopathological significance has not been determined. Sera from 212 consecutive patients with inflammatory myopathies were screened for anti-mitochondrial ant...
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Several drugs and toxic substances can cause muscular abnormalities and are frequent causes of acquired myopathies. We present a series of 32 patients, predominance of young adult patients, diagnosed with toxic myopathy. The most common substances inducing myopathy were corticosteroids (56.2%) followed by the propoxyphene, neuroleptics, zidovudine and drug-induced hypokalemia. The investigation...
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Idiopathic inflammatory myopathies (IIM) include the main subgroups polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM) and juvenile DM (JDM). The mentioned subgroups are characterised by inflammation of skeletal muscles leading to muscle weakness and other organs can also be affected as well. Even though clinically significant heart involvement is uncommon, heart disease is ...
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This study aimed to determine the expression pattern of the adenosine receptor (AR) subtypes A2A, A2B, and A3 in human idiopathic inflammatory myopathies (IIMs). A total of 27 patients diagnosed with IIMs were evaluated in this retrospective study, including 14 dermatomyositis, 9 polymyositis, and 4 inclusion body myositis cases. Fourteen control subjects without clinical and histological neuro...
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ژورنال
عنوان ژورنال: Seminars in Arthritis and Rheumatism
سال: 2021
ISSN: 0049-0172
DOI: 10.1016/j.semarthrit.2021.05.019